The Cardiovascular Disease (CVD) Epidemic

  • Heart disease is the leading cause of death in the US; stroke is third.
  • 50% of cardiovascular events strike in patients with unremarkable lipid levels.
  • 780,000 strokes occur in Americans each year.
  • Strokes kill twice as many women a year as breast cancer.
  • Strokes are the leading cause of serious, long-term disability.
  • Direct and indirect costs for CVD in the US are estimated at nearly $450 billion a year.
  • Current studies demonstrate LDL has proven NOT to be a reliable predictor of stroke risk.

Lp-PLA2 Mechanism of Action

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